TY - JOUR AU - Koç, İrem AU - Kapucu, Yasemin AU - Kıratlı, Hayyam PY - 2023/03/26 Y2 - 2024/03/29 TI - Clinical Features and Treatment Results of Conjunctival Melanoma: Cross-Sectional Study JF - Acta Medica JA - Acta Medica VL - 54 IS - 1 SE - Original Article DO - 10.32552/2023.ActaMedica.877 UR - https://www.actamedica.org/index.php/actamedica/article/view/877 SP - 54-58 AB - <p><strong>Purpose:</strong> Our aim in this study is to report the clinical features and treatment results of patients with conjunctival melanoma (CM) diagnosed in our clinic in the last 20 years.</p><p><strong>Materials and Methods:</strong> Demographic information, tumor diameter, accompanying melanosis, presence of recurrence and survival data were obtained retrospectively from the records of patients who had histopathologically confirmed CM diagnosis.</p><p><strong>Results:</strong> Conjunctival melanoma was detected in 84 eyes of 84 patients with a mean age of 61.5±24.6 years. In total 45.2% of the patients were female and 54.8% were male. The two most common primary lesion locations were limbus in 23.8% and bulbar conjunctiva in 22.6% of the patients. In ophthalmological evaluation, 46.3% of the patients had concomitant primary acquired melanosis. Appropriate surgical excision to the extent of the disease was performed primarily in all patients. After a median follow-up of 55 months, local recurrence rate was 45.2%, while the survival rate was found to be 74.3%.</p><p><strong>Conclusion:</strong> Conjunctival melanoma is a malignant neoplasm seen in advanced adulthood, often involving the bulbar surface of the conjunctiva. Even using the standard surgical approach, CM is associated with a 45.2% local recurrence rate and a 25.7% mortality rate. In our study, there was no clinical parameter that showed a statistically significant relationship with survival.</p> ER -